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Yes you can do so but Executing JavaScript from a string is an enormous security risk.
// get value as string from your file
let formula = getFromFile() // 'x * 5 + y'
// get x and y from user
let x = getXFromUser() // 1
let y = getYFromUser() // 2
console.log(eval(formula)) // 7
Check out documentation for eval
here.
Source:stackexchange.com