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Use the --no-site-packages
option to prevent the virtual environment from having access to all the packages on your system.
virtualenv --no-site-packages venv
If you don’t need the Brlapi for your Django app, try removing the Brlapi==0.5.5 line from your requirements.txt
document. Then, commit the change:
git add requirements.txt
git commit
git push heroku master
Source:stackexchange.com