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You can also use Domain Authentication to enable all addresses from that domain, incl your norepl@mydomain.com.
When sending email, you must set Domain Name System (DNS) records on the domain to:
- Communicate to receiving email servers that you own the domain the email was sent from.
- Verify that you have given the sending email server permission to send email on behalf of the domain.
PS: This might also help you in avoiding that your mails get flagged as spam.
Source:stackexchange.com