[Django]-PermissionError: [Errno 1] Operation not permitted: '/Users/<local_path>/venv/pyvenv.cfg'

I was facing the same problem and after a few searching i found a error with cron permissions.

This is how i solved:

• Go to System Preferences -> Security & Privacy – Privacy -> Full Disk
  Access

• Click on the + icon to add an item

  If the lock appears locked, click on him to unlock with your user password

• Press Command + Shift + G to open a dialog

• Type /usr/sbin/cron and press Enter

• Search and select the cron file and click Open

Okay, now it should work.

The reason for the PermissionError is that the Python virtual environment is placed in the user directory.
If you put the virtual environment in a system directory, such as /opt, there will be no problem. See example below:

$ sudo mkdir /opt/myvenv
$ cd /opt/myvenv
$ sudo python3 -m venv .venv

$ mkdir ~/workspaces/myapp
$ cd ~/workspaces/myapp
$ cat <<EOF> demo.py
> with open('/Users/username/workspaces/myapp/demo.txt', 'a+') as f:
>     f.write('Hello, cron.\n')
> EOF

$ crontab -e

$ crontab -l
* * * * * /opt/myvenv/.venv/bin/python /Users/username/workspaces/myapp/demo.py  >> /Users/username/workspaces/myapp/demo.log 2>&1

$ ls -al
total 24
drwxr-xr-x    5 username  staff   160B  6 20 09:24 .
drwxr-xr-x  136 username  staff   4.3K  6 20 09:18 ..
-rw-r--r--    1 username  staff     0B  6 20 09:23 demo.log
-rw-r--r--    1 username  staff   117B  6 20 09:23 demo.py
-rw-r--r--    1 username  staff    11B  6 20 09:24 demo.txt