[Answered ]-Is there any method in Django or Python For prediction?

You could use a catch-all URL, e.g. put url(r"^(.*)$" as your last entry in urls.py and then use some string similarity measure to find a likely url. See this question for examples. Or this one for more of them.

Or perhaps just a simple startswith() loop over known urls will do?

Your view probably should return a response with a redirect (result code 302 or 303) if there is a single match – and if there are none (or multiple) a 404 page with list of possible matches is the way to go.