[Answered ]-Install mod-wsgi in a poetry virtual environment

If Apache mod_wsgi refuses to use the virtual env, you can try gunicorn or uwsgi instead. Both can serve HTTP. You can use Apache with mod_proxy to forward requests or you can consider directly exposing uwsgi or gunicorn. You can also mod_uwsgi to Apache talk over uwsgi protocol. Nginx supports uwsgi too.

Doesn’t look like Apache knows about Poetry or the virtual environment. I would try wrapping your wsgi.py in a shell script that uses Poetry to start wsgi.py. That way Apache can use the wrapper script which will force it to use the right Python version.

#!/bin/sh
exec poetry run python wsgi.py

WSGIScriptAlias / /var/www/html/GameManager/app/my-script-that-calls-poetry-run-python-wsgi-py.sh