[Django]-How to get Django url correctly?

I would suggest doing whatever you can to get your prod and dev as identical as possible, however if thats not possible you could use separate urlpatterns for the development environment.

Assuming you have a settings.DEBUG set, try the following:

extra_patterns = patterns('',
    (r'enroll/$', 'enroll'),
)

if settings.DEBUG:
    urlpatterns = patterns('', (r'^', include(extra_patterns)))
else:
    urlpatterns = patterns('', (r'^activity/', include(extra_patterns)))