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This is not a function of Django at all, but of whatever system is being used to serve Django. Usually that’ll be wsgi via something like mod_wsgi or a standalone server like gunicorn, but it might be something completely different like FastCGI or even plain CGI.
The point is that all these different systems have their own models that determines process lifetime. In anything other than basic CGI, any individual process will certainly serve several requests before being recycled, but there is absolutely no general guarantee of how many – the process might last several days or weeks, or just a few minutes.
One thing to note though is that you will almost always have several processes running concurrently, and you absolutely cannot count on any particular request being served by the same one as the previous one. That means if you have any user-specific data you want to persist between requests, you need to store it somewhere like the session.