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Yes this is possible, it depends entirely on the webserver you are going to use so I can’t give you a general tutorial.
Using the currently documented method of deploying Django with mod_wsgi
(personally I’d recommend using Gunicorn with Nginx) you can follow this tutorial:
https://docs.djangoproject.com/en/1.7/howto/deployment/wsgi/modwsgi/
The only change you are going to have to make is the WSGIScriptAlias /...
line:
In your case it would be something like this:
WSGIScriptAlias /django/ /path/to/mysite.com/mysite/wsgi.py
Source:stackexchange.com