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Directly typing python, just starts the interpreter.
Using manage.py within a django project sets the environment so that you can interact with your project objects in the shell. As noted here:
We’re using this instead of simply typing “python”, because manage.py
sets the DJANGO_SETTINGS_MODULE environment variable, which gives
Django the Python import path to your mysite/settings.py file.
👤Carlos Mermingas
Source:stackexchange.com