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The problem is due to changes introduced in Xcode 5.1 and due to the way the Apple-supplied system Python 2.7 is built. Try adding these environment variable values before running pip:
export CFLAGS=-Qunused-arguments
export CPPFLAGS=-Qunused-arguments
See clang error: unknown argument: '-mno-fused-madd' (python package installation failure) for more information.
UPDATE [2014-05-16]: As expected, Apple has fixed this problem with updated system Pythons (2.7, 2.6, and 2.5) in OS X 10.9.3 so the workaround is no longer necessary when using the latest Mavericks and Xcode 5.1+. However, as of now, the workaround is still required for OS X 10.8.x (Mountain Lion, currently 10.8.5) if you are using Xcode 5.1+ there.
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Building on Ned’s answer:
Since I don’t want to use sudo to install packages (I am using virtual environments) or affect my golbal environment, I added the two variables to the single execution of pip install:
CFLAGS=-Qunused-arguments CPPFLAGS=-Qunused-arguments pip install -r requirements.txt
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