[Fixed]-Can't get MySQL/MariaDB to work with Django 1.10.1 and Python 3.5 on Fedora 24?

This is why you should install Python packages via pip, not your OS package manager. MySQLdb is not available for Python 3, as you can see from the error when you tried via pip3.

The reason you had issues installing mysql-client is presumably because you need the python-devel package, or whatever the Fedora equivalent is; that would be a dnf install.

However since you did succeed with mysql-connector, you can use that; you need to configure Django to use it as shown in that library’s documentation, by replacing 'django.db.backends.mysql' with 'mysql.connector.django'.