[Django]-Django exclude query, can i pass multiple parameters?

You can do this, but then you say exclude all Demos that have company__isnull=True, and as email 'abc@gmail.com'. This thus means that if only one of the two conditions is met, it is not excluded.

You can work with Q objects, like:

from django.db.models import Q

Demo.objects.exclude(
    Q(company__isnull=True) |
    Q(email='abc@gmail.com')
)

But it is likely more readable with:

Demo.objects.exclude(
    company__isnull=True
).exclude(
    email='abc@gmail.com'
)

this will thus exclude items for which company is NULL and exclude items for which email is 'abc@gmail.com'. So here we exclude it from the moment at least one condition is satisfied.

Queries are lazy, nothing happens until you try to pull data from it, so there’s no downside to using .exclude() more than once.

Demo.objects.exclude(
    company__isnull=True
).exclude(
    email='abc@gmail.com'
)

Another way is to use Q objects that can be combined using the & and | operators.

# Import
from django.db.models import Q

# Exclude query
exclude_query = Q()
exclude_query.add((~Q(company__isnull=True), Q.OR)
exclude_query.add((~Q(email="abc@gmail.com"), Q.OR)

# Get final objects which excludes email "abc@gmail.com" and null companys
result = Demo.objects.filter(exclude_query)

Your logic is not right, this is excluding every Demo that has no company and has an email of abc@gmail.com. You may want to chain exclude() calls instead.

Demo.objects.all().exclude(company__isnull=True).exclude(email="abc@gmail.com")